nad+

nicotinamide adenine dinucleotide · sirtuin cofactor

Central coenzyme of cellular bioenergetics. Activates sirtuins (SIRT1–7) involved in DNA repair, inflammation and energy metabolism.

vial size

for laboratory use only — not for human consumption. ships from tallinn within 24 h, EU delivery in 48 h.

research monograph

what the literature shows.

A condensed monograph drawn from preclinical and clinical literature. Cited mechanisms, specifications and the research case for nad+.

01 · mechanism of action

NAD+ (nicotinamide adenine dinucleotide) is one of the most central molecules in cell biology and plays a key role in aging research. In groundbreaking studies by David Sinclair (Harvard), aged mice showed measurable rejuvenation of muscle physiology after NAD+ supplementation: mitochondrial density rose to levels of young animals. Further animal studies showed lifespan extensions of 5–10 % in mice via NMN/NR precursors. Mechanistically NAD+ activates sirtuins (SIRT1–7) which coordinate DNA repair, dampen inflammation and optimize energy metabolism. In Alzheimer mouse models supplementation improved cognitive performance and reduced amyloid-β accumulation.

02 · product specifications

Each vial contains 500 mg NAD+ as lyophilized powder at ≥ 99.0 % purity (HPLC). The high unit quantity enables a wide range of biochemical assays, enzyme kinetics studies and cell-culture experiments. Storage at −20 °C, light-protected.

03 · research advantages

Sits at the centre of modern longevity research and is intensively studied by Sinclair, Auwerx and Brenner. The 500 mg unit enables extensive experimental series and biochemical characterizations. Indispensable for any aging-research laboratory.

datasheet

full specification.

Identity, mass, purity reference and storage profile for the current lot of nad+. For laboratory use only.

catalog no.: PH-6001-N
cas: 53-84-9
molecular weight: 663.43 g/mol
purity (hplc): ≥ 99.0 % (hplc)
endotoxin: < 0.5 eu/mg
appearance: white lyophilized powder
reconstitution: bacteriostatic water · 0.9 % nacl
stability (reconstituted): 14 d at 2–8 °c
shelf life (lyophilized): 24 m at −20 °c
storage: −20 °c, protect from light
current lot: nad-260117
current exp.: 07 / 2027
lead time: ships in 24 h

same series · longevity

from the same bench.

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